CURCUMIN COMPLEX 1500mg 20 SINGLE DOSES - Natiris
CURCUMIN COMPLEX 1500mg 20 SINGLE DOSES from Natiris
With Anti-tumor and Anti-invasion effect.
- Chemopreventive Effect
CHEMIOPREVENTIVE EFFECTS OF CURCUMIN
Curcumin has been shown to protect against skin, oral, intestinal and colon carcinogenesis and also to suppress metastasis in a variety of tumors in animal models.
It also inhibits the proliferation of cancer cells, keeping them in the various phases of the cell cycle and inducing apoptosis. In addition, curcumin has an ability to inhibit cancer bioactivation through the suppression of specific cytochrome P450 isoenzymes, as well as to induce the activity or expression of stage II carcinogenic detoxification enzymes.
Chemoprevention is the attempt to use natural and synthetic compounds to intervene in the early precancerous stages of carcinogenesis, before malignancy manifests itself.
A good example is curcumin, which can act at all stages of carcinogenesis. The chemopreventive properties of curcumin have been extensively investigated and are well documented.
Curcumin exerts potential chemopreventive activities in various animal tumor models through multiple molecular mechanisms underlying the targeting of all stages of carcinogenesis.
EFFECTS: ANTI-TUMOR, ANTI-INVASION AND ANTI-METASTATIC OF CURCUMIN
Curcumin inhibits tumor cell metastasis, demonstrated in vitro as well as in in vivo models, and the possible mechanism is the inhibition of matrix metalloproteases.
Curcumin shows cytotoxic potential against tumor cells both in vitro and in vivo. The main mechanism of cytotoxicity is the induction of apoptosis. Curcumin activates and represses several signaling events that are necessary for normal cell function.
It modulates these signaling pathways in such a way that the final events will be the death of these cells.
CURCUMIN AS AN ANGIOGENESIS INHIBITOR
Curcumin, a new low molecular weight compound, has been shown to inhibit carcinogenesis in different organs and the common link between these actions is its anti-angiogenic effect.
Curcumin is a direct inhibitor of angiogenesis and also regulates the production of pro-angiogenic proteins such as vascular endothelial growth factor and basic fibroblast growth factor.
All of these studies and the lack of toxicity point to curcumin for enormous potential as an antiangiogenic.
Purified water; Phytosomes (Vegetable Phospholipids); Curcuma longa (Curcumin); Sodium benzoate; Potassium sorbate.
Dosage and Administration:
Take 2 servings a day, 1 at breakfast and 1 at dinner, simple or diluted in a glass of water or another drink.
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